OC-0589 RBE-weighted dose in carbon ion therapy: impact of the RBE model translation on clinical outcomes
نویسندگان
چکیده
منابع مشابه
Preliminary calculation of RBE-weighted dose distribution for cerebral radionecrosis in carbon-ion treatment planning.
Cerebral radionecrosis is a significant side effect in radiotherapy for brain cancer. The purpose of this study is to calculate the relative biological effectiveness (RBE) of carbon-ion beams on brain cells and to show RBE-weighted dose distributions for cerebral radionecrosis speculation in a carbon-ion treatment planning system. The RBE value of the radionecrosis for the carbon-ion beam is ca...
متن کاملRBE and related modeling in carbon-ion therapy.
Carbon ion therapy is a promising evolving modality in radiotherapy to treat tumors that are radioresistant against photon treatments. As carbon ions are more effective in normal and tumor tissue, the relative biological effectiveness (RBE) has to be calculated by bio-mathematical models and has to be considered in the dose prescription. This review (i) introduces the concept of the RBE and its...
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Recently, proton therapy is used as one of the effective methods for treating various types of cancer in clinical treatment. An appropriate formalism to obtain relative biological effectiveness values for treatment planning studies is needed in this hadrontherapy technique. Hereby, the quantity of biological dose, instead of using the physical doses, is introduced to evaluate the biological eff...
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PURPOSE A method was developed to convert clinically prescribed RBE (Relative Biological Effectiveness)-weighted doses from the approach used at the Heavy-Ion Medical Accelerator (HIMAC) at the National Institute of Radiological Science, Chiba, Japan, to the LEM (Local Effect Model)-based TReatment planning for Particles (TRiP98) approach used in the pilot project at the GSI Helmholtzzentrum, D...
متن کاملAn interface to calculate neutron RBE values using RBE tables based on the Local Effect Model
The ALLEGRO European project aims to give a unified and consistent description as well as recommendations to be applied in estimating the risk of radiation therapy to the healthy tissue. For a complete description of radiation field, neutrons and photons are also to be considered and their dose needs to be estimated. In the target region the dose contribution of these neutral particles remains ...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2019
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(19)31009-6